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HCV infection can induce ROS-mediated oxidative stress, leading to the formation of 8-hydroxydeoxyguanosine (8-OHdG), which is an indicator of oxidative DNA damage 83

Astrocyte-derived lactate aggravates brain injury of ischemic stroke in mice by promoting the formation of protein lactylation

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2c), consistent with previous observations 4,5,17

Most DHEA is sulfated before being released into the bloodstream and circulates as DHEA-sulfate (DHEA-S)